Best Cannabis Strains for Fibromyalgia

Fibromyalgia is a difficult condition to live with, but as we’ve learned from Leafly reviewers, cannabis can offer respite. It makes sense when you look at some of the symptoms fibro sufferers face:Cannabis and Depression

There isn’t a lot of research on cannabis as a treatment for fibromyalgia, but clinical studies using synthesized THC for symptom management shows promising results. Still, there’s plenty of anecdotal evidence in Leafly’s strain reviews alone to show that cannabis is certainly providing much needed relief to many of those willing to experiment. These 10 strains, according to our user-submitted strain data, seem to be doing the trick.

Keep in mind, relief is not limited to these strains alone. There a lot – and we mean a lot – of strains that can treat painfight fatiguereduce depressionand anxietysharpen focus, and crush insomnia. Consider trying other high-CBD strains, or cannabis in various other forms like ediblestopicals, or ingestible oils. Everyone’s body is different, so the key is to try different strains and products to see what works best for you.

What are the Best Cannabis Strains for Pain?


Blue Dream

Leafly Blue Dream hybrid cannabis strain tile Leafly Blue Dream hybrid cannabis strain effects

Given the sheer volume of strain reviews available for Blue Dream, it’s no wonder that we found so many positive reports associated with this sativa-dominant hybrid from fibro patients. However, that’s not a reason to discount the therapeutic potential of this coveted berry-flavored flower; Blue Dream is known to exhibit high levels of the relaxing terpene myrcene as well as CBG, a cannabinoid known to reduce inflammation and fight insomnia. Not only that, Blue Dream delicately lifts the mood to new heights, letting you forget about the aches and worries that were keeping you down.

“Blue Dream is my go-to strain for my everyday fibromyalgia pain and muscle spasm medicine, it is gentle enough to use [every] day and throughout the day. It is a nice hybrid, with the muscle spasm easing effects of [an] indica, and the euphoric, headache easing effects of a sativa without anxiety effects. I use it when I wake up to get moving, and even use it to help me sleep.” –


Leafly Harlequin sativa cannabis strain tile Leafly Harlequin sativa cannabis strain effects

With the painkilling power of THC and CBD combined, this sativa is the perfect way to start your day. If you’re sensitive to THC, you’re in luck: Harlequin’s high-CBD content helps curb the psychoactive and anxious side effects of THC, letting you go about your day without that dizzying euphoria that some unaccustomed users find distracting or unpleasant.

“I take three puffs and get a wonderful body high that takes my pain away. It’s not that I don’t notice it anymore…it feels like it’s gone. It makes me SO happy to not feel my pain. Note that I have fibromyalgia and degenerative disc in my lower back, to for me to not be feeling my pain seems like somewhat of a miracle.” –



Leafly Cannatonic hybrid cannabis strain tile Leafly Cannatonic hybrid cannabis strain effects

In further testament to the power of high-CBD strains, Cannatonic is the third most celebrated strain from Leafly users with fibromyalgia. It’s only mildly psychoactive due to its CBD dominance, making it an excellent choice for new users. However, even veterans will appreciate this hybrid’s ability to crush pain, anxiety, muscle spasms, and a myriad of other symptoms.

“I am taking this for Fibromyalgia. This has been the most helpful strain I have found in clearing my mind. Less mind clutter leads to more mental and physical energy.” –


Critical Mass

Leafly Critical Mass indica cannabis strain tile Leafly Critical Mass indica cannabis strain effects

Critical Mass is a heavy indica strain whose tingly full-body effects radiate throughout the body, swiftly bowling down pain and stress. This strain sometimes expresses itself with enhanced levels of CBD for even better pain relief. Also preferred for treating depression, insomnia, and muscle spasms, Critical Mass is definitely a strain you’ll want in your medicine cabinet.

“My body felt nice and relaxed for the first time in [I don’t know] how long and for sure helped me sleep. Helped with my TMJ too! If you have fibromyalgia issues like I do it’s definitely one to try!” –


Tahoe OG

Leafly Tahoe OG Kush hybrid cannabis strain tile Leafly Tahoe OG Kush hybrid cannabis strain effects

This is the strain you’ll need for when your fibromyalgia symptoms are keeping you up at night. Tranquilizing and dreamy, Tahoe OG is an indica-dominant strain that leads muscles into blissful relaxation, melting the pain and tension out of them.

“This will give the pain killing effects need for heavy pain, as well as give a sedative effect, so one can go to sleep. [It’s] one of the top ten strains I use for my condition.” –


Granddaddy Purple

Leafly Granddaddy Purple indica cannabis strain tile Leafly Granddaddy Purple indica cannabis strain effects

Guiding you into relief with a sweet berry and grape flavor, Granddaddy Purple is a classic indica strain with potent painkilling properties. Like Blue Dream, GDP boasts high levels of myrcene and CBG to help relax muscles and control pain. Not only does this sweet-tasting indica treat physical symptoms, its pacifying euphoria loosens the grip of stress, anxiety, and depression to help you stay positive.

“I finally decided to roll a joint of this and some Tahoe OG, and now I’m free of cramps, muscle spasms, shooting pain, nausea, anxiety, etc…It’s rare that I find a strain that will completely help with medical problems, but also help me be happy, become more creative, and stay awake.” –


GSC (f.k.a Girl Scout Cookies)

Leafly GSC (f.k.a Girl Scout Cookies) hybrid cannabis strain tile Leafly GSC (f.k.a Girl Scout Cookies) hybrid cannabis strain effects

Coveted for its potency, flavor, and quality of effect, it’s no wonder that fibro patients also found something to love about this award-winning hybrid. GSC (f.k.a Girl Scout Cookies) is known to have a high THC content, so if you’re new to cannabis or sensitive to THC, be sure to dose low and slow with this hybrid powerhouse.

“I bought this strain for pain relief and it worked quite well. I suffer from fibro & arthritis and after smoking this for the first time, it seemed to work as well as some pain pills.” – TONYROSEITTI



Leafly Blueberry indica cannabis strain tile Leafly Blueberry indica cannabis strain effects

Indicas are wonderful pain relievers, but it isn’t often you find one with a flavor as strong and sweet as Blueberry. Named for its unmistakable ripe berry aroma, this indica delivers a nuanced effects that mellows everything from physical pain to emotional anguish caused by fibromyalgia.

“Was in so much body pain today due to fibromyalgia, so I picked up Blueberry wax this afternoon…can safely say this is the best strain for body and migraine pain I’ve tried so far. I melted into my bed, very dreamy effect.” – cholladay


Bubba Kush

Leafly Bubba Kush indica cannabis strain tile Leafly Bubba Kush indica cannabis strain effects

The symptoms of fibromyalgia are multifaceted, but thankfully, so are the effects of Bubba Kush. Muscles relax. Eyelids heavy. The mind goes from a running pace to walking. Bubba Kush bestows its gift of relief alongside a sweet, earthy coffee aroma with subtle woody notes that will keep you coming back for more even after your symptoms subside.

“Helps me sleep great which is godsend for severe fibromyalgia…working great for my awful bee stinging feeling nerve pain!” – Anonymous



Leafly Headband hybrid cannabis strain tile Leafly Headband hybrid cannabis strain effects

Named for its hugging cerebral sensations some refer to as the “halo effect,” Headband is a favorite for those suffering from headaches. But that’s not the only type of relief this fragrant hybrid has to offer. Headband’s rich terpene profile gives rise to a spectrum of benefits, including stress reduction, mood enhancement, a feeling of wakefulness and focus, and muscle relaxation.

“It’s a great strain, knocked out my knee pain that is causing a fibromyalgia flare up. It’s definitely is easing the flare up as well and the migraine associated with it.”

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