Glutamate and aspartame can improve the transmission of nerve signals of pain by increasing the action of the neurotransmitter glutamate.
Other nutrients can positively modulate the neurotransmission of glutamate and, therefore, reduce pain, says Kathleen Holton. With vitamins B6.
Vitamin B6 acts as a cofactor for an enzyme that converts glutamate (an excitatory neurotransmitter) into GABA (an inhibitory neurotransmitter).
The deficiency of this vitamin can lead to higher levels of glutamate and reduced levels of GABA, which promotes the excitotoxicity (excessive transmission of glutamate that has toxic effects in the signal receptor neurons) in the central nervous system (brain and spinal cord) ).
Magnesium and zinc
These two minerals play a key role in the regulation of the major glutamate receptor, the NMDA receptor. Therefore, low levels of magnesium and zinc can contribute to the increase in pain.
According to several studies, an omega-3 deficiency increases excitotoxicity.
Mainly, the two dietary antioxidants are vitamin C and vitamin E.
We also find other antioxidants in vegetables and fruits, such as resveratrol grapes and green tea polyphenols.